Computer application for simulation of gene regulatory network
Citation APA 7:
Simov, O., Dika, A., & Percinkova, B. (2010). Computer application for simulation of gene regulatory networks. International Journal of Computer Science and Network Security, 10(8), 193–198.
Citation Harvard:
Simov, O., Dika, A. and Percinkova, B. (2010) ‘Computer application for simulation of gene regulatory networks’, International Journal of Computer Science and Network Security, 10(8), pp. 193–198.
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| Article Тitle | Computer application for simulation of gene regulatory network |
| Journal | International Journal of Computer Science and Network Security (IJCSNS) |
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| Date Deposited | 22.9.2010 12:13 |
Citation APA 7:
Simov, O., Dika, A., & Percinkova, B. (2010). Computer application for simulation of gene regulatory networks. International Journal of Computer Science and Network Security, 10(8), 193–198.
Citation Harvard:
Simov, O., Dika, A. and Percinkova, B. (2010) ‘Computer application for simulation of gene regulatory networks’, International Journal of Computer Science and Network Security, 10(8), pp. 193–198.
Abstract
The paper presents a computer application for simulating gene regulatory networks using Boolean and extended Boolean models. The Boolean model analyses state transitions, attraction basins, periodic cycles, Hamming distances, and the effects of small perturbations. The extended model calculates protein concentrations over specified time steps from defined initial conditions. Both models support randomly generated networks and networks configured by the user.
Keywords:
Gene regulatory networks; Boolean networks; computer simulation; protein concentration; basins of attraction.